Publikace detail

Optimization of Paced AV Delay Using Atrial Contribution Index

Autoři: Měšťan M | Kvasnička Jiří

Rok: 2008

Druh publikace: odborná kniha

Název nakladatele: Nova Science Publishers

Místo vydání: Hauppauge, New York, USA

Strana od-do: nestránkováno

Tituly:

Jazyk	Název	Abstrakt	Klíčová slova
cze	Optimalizace AV zpoždění při stimulační léčbě s použitím indexu atriální kontribuce	Kniha pojednává o optimalizaci AV zpoždění při stimulační léčbě s použitím indexu atriální kontribuce
eng	Optimization of Paced AV Delay Using Atrial Contribution Index	The hemodynamic effect of the atria on the net performance of the heart is called atrial contribution (AC). AC is either linked to ventricular filling or to the systolic function of the heart, i.e. to the systolic volume or cardiac output. Several noninvasive methods for the quantification of AC are described in literature but none of them are routinely used in cardiac pacing centres due to the time-consuming nature of the methods, the limited reproducibility of measured values and observer dependency. The aim of these studies was to develop a method for determining optimal AV delay in patients treated by dual chamber pacing using an index (ACSp) that quantifies atrial contribution to the systolic volume of the left ventricle. The new method is based on the quantitative analysis of a beat to beat decrease in the amplitude of the pulse oximetry signal (SpO2). The change in the amplitudes is induced by a sudden drop of the stimulus to the right atrium, while maintaining the rate of ventricular stimuli at a constant level. The obtained ACSp is given as a percentage of the pulse amplitude of SpO2. The method is independent of the observer, noninvasive and relatively fast. In a group of 47 patients, remarkable similarities between ACSp and another atrial contribution index estimated using the tracings of invasively registered aortal pressure were demonstrated. In all investigated AV intervals of 50 to 250 ms, significant interindividual variability of ACSp was discovered. The poorest hemodynamic effect was seen at AV delay of 50 ms (median ACSp of 10.4 % from 97 subjects). In 150 subjects, the following values of ACSp were obtained at AV delay of 200 ms: median 30 %, minimum 3.6 % and maximum 80.4 %. An increase in ACSp follows reduction of preload induced by administration of furosemide. This suggests that when preload decreases cardiac output is preserved by an increase in AC enforced by sympathetic activation.	Optimization of Paced AV Delay Using Atrial Contribution Index

Vyhledávání

Přihlášení pro studenty

Přihlášení pro zaměstnance

Publikace detail

Katedry

Klinická pracoviště

Jak nás najdete?

Služby

Často hledáte